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Vitamin C

Author: Sophia

what's covered
In this lesson, you will learn about vitamin C. Specifically, this lesson will cover:

Table of Contents

1. Vitamin C (Ascorbic Acid)

Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that plays a key role in several vital bodily functions. Vitamin C is a powerful antioxidant, which means that it helps neutralize free radicals that cause oxidative stress and damage cells. This vitamin also plays a crucial role in the production of collagen, which helps maintain the health of your skin, blood vessels, bones, and cartilage. Vitamin C supports and boosts the immune system to fight off infections, accelerates the healing of wounds, bruises, and cuts, as well as enhances the absorption of non-heme iron (the type of iron found in plant-based foods).

terms to know
Vitamin C
A vitamin found in food and used as a dietary supplement. It is used to treat and prevent scurvy. It is also known as ascorbic acid and L-ascorbic acid.
Non-heme iron
The type of iron found in plant-based foods.

1a. Dietary Sources of Vitamin C

Vitamin C is abundant in many fruits and vegetables. Some examples are citrus fruits, berries, kiwi, bell peppers, leafy greens, and tomatoes. Because vitamin C is water-soluble and sensitive to heat, cooking can cause it to degrade. Raw or lightly cooked fruits and vegetables retain the most vitamin C.

1b. Dietary Reference Intake for Vitamin C

Most people can meet their vitamin C needs through a balanced diet. For those with specific deficiencies, vitamin C supplements are available. The Recommended dietary intake for vitamin C is:

  • Adults: 75 (women), 90 (men) mg/day.
  • Pregnant women: 85 mg/day.
  • Breastfeeding women: 120 mg/day.
Note that people who smoke, or use inhalants, require more vitamin C (about 35 mg more daily) due to increased oxidative stress.

1c. Deficiency, Toxicity, and Absorption of Vitamin C

Vitamin C deficiency is rare in developed countries due to the wide availability of fruits and vegetables, but it can occur in people with limited diets or certain medical conditions. Vitamin C deficiency is often called scurvy and if it is left untreated, scurvy can lead to more severe health complications. Scurvy leads to the formation of brown spots on the skin, spongy gums, and bleeding from all mucous membranes. The spots are most abundant on the thighs and legs, and a person with scurvy may look pale, feel depressed, and be partially immobilized. In advanced scurvy, there are open, suppurating wounds and loss of teeth and, eventually, death. Fortunately, scurvy can be easily reversed with vitamin C supplementation. Notable human dietary studies of experimentally induced scurvy have been conducted on conscientious objectors during WWII in Britain and on Iowa state prisoners in the late 1960s to the 1980s. These studies both found that all obvious symptoms of scurvy previously induced by an experimental diet with extremely low vitamin C content could be completely reversed by additional vitamin C supplementation of only 10 mg/day.

key concept
Vitamin C is water soluble which means excess amounts are excreted in your urine. Symptoms of vitamin C deficiency may take anywhere from one to six months to be noticeable, depending on how much vitamin C was in your body before it was restricted. Even though vitamin C is water soluble, extremely high doses may cause upset stomach and even kidney stones. The tolerable upper-level intake for adults is 2,000 mg/day which is well above the typical dietary intake and the recommended dietary intake of 65–90 mg/day.

The absorption of vitamin C can be affected by smoking, stress, and certain medications. Smoking increases oxidative stress while oral contraceptives (birth control) and certain cancer treatments reduce vitamin C levels in your body.

As mentioned earlier, vitamin C enhances the absorption of non-heme iron, so sometimes it is recommended to drink orange juice if you take an iron supplement. Vitamin C also works alongside vitamin E to protect cells from oxidative damage by neutralizing free radicals.

Vitamin C is a popular ingredient in skincare products due to its antioxidant properties. It helps brighten the skin, reduce the appearance of wrinkles, and protect against sun damage. Topical application of vitamin C can also improve skin texture and reduce hyperpigmentation.

Overall, vitamin C is essential for maintaining good health, especially for immunity, skin, and tissue repair. Getting it from a variety of fresh fruits and vegetables is usually the best way to ensure you are meeting your daily needs.

did you know
Scurvy was a major problem for sailors, especially during long voyages in the 15th through the 18th centuries, when ships went out to sea for months or even years without access to fresh food. Sailors on long voyages faced a significant risk of developing scurvy due to their limited diet. Fresh fruits and vegetables, which are rich in vitamin C, were not available on ships. Instead, sailors mostly ate preserved foods like dried meat, hardtack (a type of dry biscuit), and salted fish, which lacked vitamin C. As a result, after several months at sea, many sailors would begin to suffer from symptoms of scurvy. It was one of the leading causes of death among sailors during the Age of Exploration, as they would be at sea for long periods with no access to fresh food sources that could prevent the disease.

The connection between scurvy and vitamin C was not well understood until the 18th century. Sailors and doctors had noticed that some sailors were immune to scurvy, while others fell ill. But the exact cause was elusive. Various remedies were proposed over the centuries, with varying degrees of success, including the use of citrus fruits, vinegar, and various herbal concoctions. However, the importance of vitamin C was not fully recognized at the time.

The breakthrough came from James Lind, a Scottish naval surgeon in the 18th century. In 1747, Lind conducted an experiment where he tested different treatments for scurvy on twelve sailors suffering from the disease. He divided the sailors into groups, giving each group a different remedy, such as cider, vinegar, seawater, or a variety of fruits and herbs. Lind's results showed that the sailors who were given citrus fruits (oranges and lemons) recovered far more quickly than the others. This discovery suggested that the lack of vitamin C in the sailors’ diet was the root cause of scurvy. Lind published his findings, but it took many more years before the British Navy fully adopted the practice of providing sailors with citrus fruits.

Although Lind's discovery was groundbreaking, it was not immediately accepted. By the 1790s, the British Navy had adopted the practice of giving sailors lime juice—which led to the nickname "limeys"—as a preventive measure against scurvy. This simple intervention saved countless lives, and the British Navy became one of the most powerful in the world during the Age of Sail, partly because it was able to maintain a healthier, more capable crew. The practice of providing sailors with lime juice continued throughout the 19th century.

The connection between scurvy and vitamin C was finally understood in the early 20th century. Scientists discovered that ascorbic acid (vitamin C) was the missing nutrient that prevented scurvy. It was found that vitamin C is essential for collagen production, a protein that helps maintain the structure of blood vessels, skin, and bones. Without enough vitamin C, blood vessels weaken, leading to the characteristic symptoms of scurvy, such as bleeding gums and skin bruising.

Today, we understand that scurvy is easily preventable with a diet that includes sufficient vitamin C, found in fruits like oranges, lemons, kiwis, and vegetables like bell peppers. The story of scurvy and the sailors' struggles is a reminder of the importance of nutrition in maintaining health, and it underscores how critical vitamins and minerals are for our bodies.

term to know
Scurvy
An avitaminosis resulting from lack of vitamin C, since without this vitamin, the synthesized collagen is too unstable to perform its function.

summary
In this lesson, you learned about Vitamin C or ascorbic acid. Dietary sources of vitamin C include most fruits and vegetables, especially those that are raw. Dietary reference intakes for vitamin C are usually met through eating a balanced diet. Vitamin C deficiency leads to scurvy. Scurvy leads to the formation of brown spots on the skin, spongy gums, and bleeding from all mucous membranes. Vitamin C toxicity is very rare because vitamin C is a water-soluble vitamin. Vitamin C absorption can be affected by smoking, stress, and certain medications.

Source: THIS TUTORIAL HAS BEEN ADAPTED FROM LUMEN LEARNING’S “NUTRITION FLEXBOOK”. ACCESS FOR FREE AT https://courses.lumenlearning.com/suny-nutrition/. LICENSE: creative commons attribution 4.0 international.

Terms to Know
Non-heme Iron

The type of iron found in plant-based foods.

Scurvy

An avitaminosis resulting from lack of vitamin C, since without this vitamin, the synthesized collagen is too unstable to perform its function.

Vitamin C

A vitamin found in food and used as a dietary supplement. It is used to treat and prevent scurvy. It is also known as ascorbic acid and L-ascorbic acid.