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The vertebral column is also known as the spinal column or spine. It consists of a sequence of vertebrae (singular, vertebra), each of which is separated and united by an intervertebral disc formed by connective tissue. Together, the vertebrae and intervertebral discs form the vertebral column. It is a flexible column that supports the head, neck, and body and allows for their movements. It also protects the spinal cord, which passes down the back through openings in the vertebrae.

The vertebral column originally develops as a series of 33 vertebrae. However, as you developed, certain vertebrae fused together, leaving the adult human with 24 vertebrae, plus the sacrum and coccyx. The vertebral column is subdivided into five regions, with the vertebrae in each area named for that region and numbered in descending order.
The vertebral column does not form a straight line, but instead curves. At birth, the entire vertebral column has a single anterior curvature. However, as an adult, there are four curves: two anterior and two posterior.
However, as a child learns to hold its head up, sit upright, stand, and walk, muscle tension will pull on the cervical and lumbar vertebrae and force them to curve posteriorly, forming what is called secondary curvature. The alternating curvatures in the spine cause the vertebral column to adopt an S-shape which increases the vertebral column’s strength, flexibility, and ability to absorb shock. When the load on the spine is increased, like by carrying a heavy backpack, the curvatures increase in depth (become more curved) to accommodate the extra weight. They then spring back when the weight is removed.

Disorders associated with the curvature of the spine include kyphosis (an excessive posterior curvature of the thoracic region), lordosis (an excessive anterior curvature of the lumbar region), and scoliosis (an abnormal, lateral curvature, accompanied by twisting of the vertebral column).
Developmental anomalies, pathological changes, or obesity can enhance the normal vertebral column curves, resulting in the development of abnormal or excessive curvatures. Kyphosis, also referred to as humpback or hunchback, is an excessive posterior curvature of the thoracic region. This can develop when osteoporosis causes weakening and erosion of the anterior portions of the upper thoracic vertebrae, resulting in their gradual collapse. Lordosis, or swayback, is an excessive anterior curvature of the lumbar region and is most commonly associated with obesity or late pregnancy. The accumulation of body weight in the abdominal region results in an anterior shift in the line of gravity that carries the weight of the body. This causes an anterior tilt of the pelvis and a pronounced enhancement of the lumbar curve.
Scoliosis is an abnormal, lateral curvature accompanied by twisting of the vertebral column. Compensatory curves may also develop in other areas of the vertebral column to help maintain the head positioned over the feet. Scoliosis is the most common vertebral abnormality among girls. The cause is usually unknown, but it may result from weakness of the back muscles, defects such as differential growth rates in the right and left sides of the vertebral column, or differences in the length of the lower limbs. When present, scoliosis tends to get worse during adolescent growth spurts. Although most individuals do not require treatment, a back brace may be recommended for growing children. In extreme cases, surgery may be required.
Excessive vertebral curves can be identified while an individual stands in the anatomical position. Observe the vertebral profile from the side and then from behind to check for kyphosis or lordosis. Then have the person bend forward. If scoliosis is present, an individual will have difficulty bending directly forward, and the right and left sides of the back will not be level with each other in the bent position.


Within the different regions of the vertebral column, vertebrae vary in size and shape, but they all follow a similar structural pattern. A typical vertebra will consist of a body, a vertebral arch, and seven processes.
The vertebral body is the anterior portion of each vertebra and is the part that supports the body weight. Because of this, the vertebral bodies progressively increase in size and thickness going down the vertebral column. The bodies of adjacent vertebrae are separated and strongly united by an intervertebral disc.
The vertebral arch forms the posterior portion of each vertebra. It consists of four parts, the right and left pedicles and the right and left laminae. Each pedicle forms one of the lateral sides of the vertebral arch. The pedicles are anchored to the posterior side of the vertebral body. Each lamina forms part of the posterior roof of the vertebral arch. The large opening between the vertebral arch and body is the vertebral foramen, which contains the spinal cord. In the intact vertebral column, the vertebral foramina of all of the vertebrae align to form the vertebral (spinal) canal, which serves as the bony protection and passageway for the spinal cord down the back. When the vertebrae are aligned together in the vertebral column, notches between the pedicles of adjacent vertebrae form an intervertebral foramen (intervertebral, between two vertebrae), the opening through which a spinal nerve exits from the vertebral column.
Seven processes arise from the vertebral arch. Each paired transverse process projects laterally and arises from the junction point between the pedicle and lamina. The single spinous process, also referred to as the vertebral spine, projects posteriorly at the midline of the back. The vertebral spines can easily be felt as a series of bumps just under the skin down the middle of the back. The transverse and spinous processes serve as important muscle attachment sites. A superior articular process extends or faces upward, and an inferior articular process faces or projects downward on each side of the vertebrae. The paired superior articular processes of one vertebra join with the corresponding paired inferior articular processes from the next higher vertebra or the skull in the case of the first vertebra (C1). These junctions form slightly moveable joints. The shape and orientation of the articular processes vary in different regions of the vertebral column and play a major role in determining the type and range of motion available in each region.

In addition to the general characteristics of a typical vertebra described above, vertebrae also display characteristic size and structural features that vary between the different vertebral column regions. Thus, cervical vertebrae are smaller than lumbar vertebrae due to differences in the proportion of body weight that each supports. Thoracic vertebrae have sites for rib attachment, and the vertebrae that give rise to the sacrum and coccyx have fused together into single bones.
Cervical vertebrae show slight variations in their general structures that differentiate them from thoracic or lumbar vertebrae.

The thoracic vertebrae also have slight variations in their general structure that differentiate them from cervical or lumbar vertebrae.


Lumbar vertebrae similarly have slight variations in their general structure.

The sacrum is a triangular-shaped bone that is thick and wide across its superior base where it is weight-bearing and then tapers down to an inferior, non-weight-bearing apex. It is formed by the fusion of five sacral vertebrae, a process that does not begin until after the age of 20. The coccyx, or tailbone, is derived from the fusion of four very small coccygeal vertebrae. It articulates with the inferior tip of the sacrum. It is not weight-bearing in the standing position but may receive some body weight when sitting.

The bodies of adjacent vertebrae are strongly anchored to each other by an intervertebral disc. This structure provides padding between the bones during weight bearing and, because it can change shape, also allows for movement between the vertebrae. Although the total amount of movement available between any two adjacent vertebrae is small, when these movements are summed together along the entire length of the vertebral column, large body movements can be produced. Ligaments that extend along the length of the vertebral column also contribute to its overall support and stability.
Recall that an intervertebral disc is a pad of connective tissue (fibrocartilage) that fills the gap between adjacent vertebral bodies. Each disc is anchored to the bodies of its adjacent vertebrae, thus strongly uniting them. The discs also provide padding between vertebrae during weight bearing. Because of this, intervertebral discs are thin in the cervical region and thickest in the lumbar region, which carries the most body weight. In total, the intervertebral discs account for approximately 25% of your body height between the top of the pelvis and the base of the skull. Intervertebral discs are also flexible and can change shape to allow for movements of the vertebral column.
Each intervertebral disc consists of two parts. The annulus fibrosus is the tough, fibrous outer layer of the disc. It forms a circle (annulus, ring) and is firmly anchored to the outer margins of the adjacent vertebral bodies. Inside is the nucleus pulposus, consisting of a softer, more gel-like material. It has a high water content that serves to resist compression and thus is important for weight bearing. With increasing age, the water content of the nucleus pulposus gradually declines. This causes the disc to become thinner, decreasing total body height somewhat, and reduces the flexibility and range of motion of the disc, making bending more difficult.

The gel-like nature of the nucleus pulposus also allows the intervertebral disc to change shape as one vertebra rocks side to side or forward and back in relation to its neighbors during movements of the vertebral column. Thus, bending forward causes compression of the anterior portion of the disc but expansion of the posterior disc. If the posterior annulus fibrosus is weakened due to injury or increasing age, the pressure on the disc when bending forward and lifting a heavy object can cause the annulus fibrosus to permanently stretch. If the material does not break, this is considered a bulging disc and can cause compression of a spinal nerve at the point where it exits through the intervertebral foramen, with resulting pain and/or muscle weakness in those body regions supplied by that nerve. If the pressure is greater and causes the nucleus pulposus to protrude (push) posteriorly through the annulus fibrosus, it will result in a herniated disc (“ruptured” or “slipped” disc). The most common sites for disc herniation are the L4/L5 or L5/S1 intervertebral discs, which can cause sciatica, a widespread pain that radiates from the lower back down the thigh and into the leg. Similar injuries of the C5/C6 or C6/C7 intervertebral discs, following forcible hyperflexion of the neck from a collision accident or football injury, can produce pain in the neck, shoulder, and upper limb.

IN CONTEXT
Career Connection: Chiropractor
Chiropractors are health professionals who use nonsurgical techniques to help patients with musculoskeletal system problems that involve the bones, muscles, ligaments, tendons, or nervous system. They treat problems such as neck pain, back pain, joint pain, or headaches. Chiropractors focus on the patient’s overall health and can also provide counseling related to lifestyle issues, such as diet, exercise, or sleep problems. If needed, they will refer the patient to other medical specialists.
Chiropractors use a drug-free, hands-on approach for patient diagnosis and treatment. They will perform a physical exam, assess the patient’s posture and spine, and may perform additional diagnostic tests, including taking X-ray images. They primarily use manual techniques, such as spinal manipulation, to adjust the patient’s spine or other joints. They can recommend therapeutic or rehabilitative exercises, and some also include acupuncture, massage therapy, or ultrasound as part of the treatment program. In addition to those in general practice, some chiropractors specialize in sport injuries, neurology, orthopedics, pediatrics, nutrition, internal disorders, or diagnostic imaging.
To become a chiropractor, students must have 3–4 years of undergraduate education, attend an accredited, four-year Doctor of Chiropractic (D.C.) degree program, and pass a licensure examination to be licensed for practice in their state. With the aging of the baby-boom generation, employment for chiropractors is expected to increase.
Source: THIS TUTORIAL HAS BEEN ADAPTED FROM OPENSTAX "ANATOMY AND PHYSIOLOGY 2E." ACCESS FOR FREE AT openstax.org/books/anatomy-and-physiology-2e/pages/1-introduction. LICENSE: CC ATTRIBUTION 4.0 INTERNATIONAL. Accessed by October 2022.