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In this lesson, you will learn terminology related to the digestive system.
The function of the digestive system is to break down the foods you eat, release their nutrients, and absorb those nutrients into the body. The digestive system is continually at work, but people often don’t appreciate the complex tasks it performs until something malfunctions. Consider what happens when you eat an apple. You enjoy the apple’s taste as you chew it, but in the hours that follow, unless something goes amiss and you get a stomachache, you don’t notice your digestive system is working. You may be working, studying, or sleeping, having forgotten all about the apple, but your stomach and intestines are busy digesting it. By the time any waste material is excreted, the body has absorbed all the nutrients it can use from the apple. In short, whether you pay attention or not, the organs of the digestive system perform their specific functions, allowing you to use the food you eat to provide energy for your daily activities.
The figure above shows the basic structure of the human digestive tract. You will learn more about all of these structures later in this course. You can see the basic path traveled by food. Food enters the mouth, then travels through the tubular esophagus to the stomach, located around the middle of the trunk. The liver, an important organ with many functions, covers the top of the stomach and extends to the lower right side. The gallbladder is a smaller organ that is located just below the liver, with ducts extending to the liver and small intestine. The stomach connects to the small intestine, a long, tubular organ coiled in the lower abdomen. The small intestine connects to the large intestine, which rises along the right side of the abdomen (the ascending colon), runs horizontally across the abdomen above the small intestine and below the liver (the transverse colon), runs down the left side of the abdomen (the descending colon), and curves back below the small intestine before curving down to end at the anus, through which wastes exit the body. Note that the colon (including the ascending, transverse, and descending colon) makes up most of the large intestine. The pancreas is visible between the large intestine and stomach.
The table below shows common prefixes that you will encounter as you learn about the digestive system. Most of these should be familiar. Remember that many other prefixes are also used, including prefixes that you have already learned.
Term | Definition | Example | Definition of Example |
---|---|---|---|
Dys- | Abnormal | Dysphagia | Difficulty in swallowing |
Endo- | Within, in | Esophagogastroduodenoscopy (EGD) | Visualization of the esophagus, stomach, and duodenum (the first part of the intestine) using an endoscope, making it a type of endoscopy |
Sub- | Under, below | Sublingual | Under the tongue |
Many combining forms that you have already learned are relevant to learning about the digestive system. Some examples of familiar combining forms and a few new combining forms are in the table below. The table below focuses on combining forms that describe digestive system structures.
Term | Definition | Example | Definition of Example |
---|---|---|---|
Abdomin/o | Abdomen, abdominal | Abdominal region | Region of the abdomen |
An/o | Anus | Anorectal manometry | A medical test of the function of the muscles involved in producing a bowel movement (anal muscles, rectal muscles; Cleveland Clinic, 2023) |
Append/o, appendic/o | Appendix | Appendicitis | Inflammation of the appendix |
Celi/o | Abdomen, abdominal cavity | Celiac disease | A serious autoimmune disorder that can occur in genetically predisposed people, where the ingestion of gluten leads to damage in the small intestine. |
Chol/e | Gall, bile (a digestive fluid produced by the gallbladder that can emulsify lipids) | Cholecystitis | Inflammation of the gallbladder |
Cholangi/o | Bile duct | Cholangiocarcinoma | A group of cancers that affect the bile ducts that carry bile between the liver, gallbladder, and small intestine (Mayo Clinic, n.d.) |
Col/o, colon/o | Colon | Colorectal cancer (CRC) | A type of cancer that occurs in the colon or rectum |
Diverticu/o | Diverticulum (a small, bulging pouch that can form in the lining of the digestive system) | Diverticulitis | Inflammation or infection of one or more diverticula in the digestive tract |
Duoden/o | Duodenum (the first section of the small intestine, immediately beyond the stomach, leading to the jejunum) | Duodenojejunostomy | A medical procedure that creates an opening between the duodenum and jejunum (for example, to bypass a constriction; Merriam-Webster, n.d.) |
Enter/o | Intestine | Enteritis | Inflammation of the small intestine |
Esophag/o | Esophagus | Esophagitis | Inflammation of the esophagus |
Gastr/o | Stomach | Gastritis | Inflammation of the stomach |
Hepat/o | Liver | Hepatitis | Inflammation of the liver |
Ile/o | Ileum | Ileocecal valve | A sphincter muscle valve that separates the small intestine and the large intestine |
Here are more examples of combining forms that are useful to know as you learn about the digestive system.
Term | Definition | Example | Definition of Example |
---|---|---|---|
Jejun/o | Jejunum | Duodenojejunostomy | A medical procedure that creates an opening between the duodenum and jejunum (for example, to bypass a constriction; Merriam-Webster, n.d.) |
Lingu/o | Tongue | Sublingual | Under the tongue |
Or/o | Mouth | Oral | Pertaining to the mouth (e.g., oral medication is administered by mouth) |
Pancreat/o | Pancreas | Pancreatitis | Inflammation of the pancreas |
Peritone/o | Peritoneum | Peritonitis | Inflammation of the peritoneum |
Polyp/o | Polyp (a small growth) | Polypectomy | Removal of a polyp, such as precancerous polyps in the colon |
Proct/o | Rectum | Proctologist | A physician who specializes in diagnosing and treating disorders of the rectum and anus |
Steat/o | Fat | Steatohepatitis | Inflammation of the liver caused by excess fat buildup (Mayo Clinic, 2025) |
Xer/o | Dry | Xerostomia | Dry mouth |
In addition to prefixes and combining forms, there are many suffixes that are useful in discussing the digestive system. The table below includes familiar suffixes and a few new suffixes that will be helpful.
Term | Definition | Example | Definition of Example |
---|---|---|---|
-cele | Hernia, protrusion | Omphalocele | A medical condition in which a baby is born with their abdominal organs outside of their body (protruding); surgery is required to treat the condition; Cleveland Clinic, 2024) |
-lith | Stone | Cholelithiasis | The formation of gallstones (small, hard crystalline masses) in the gallbladder |
-malacia | Softening | Osteomalacia | Softening of the bones, which can be caused by certain gastrointestinal conditions, such as celiac disease, that can result in vitamin D malabsorption (Minisola et al., 2020) |
-megaly | Enlargement | Hepatomegaly | Enlargement of the liver |
-osis | Condition | Diverticulosis | The condition of having diverticula in the colon |
-pepsia | Digestion | Dyspepsia | Indigestion (marked by epigastric pain, burning, and nausea) |
-phagia | Eating or swallowing | Dysphagia | Difficulty in swallowing |
-stomy | Creating an opening | Colostomy | A surgical procedure that brings one end of the large intestine out through the abdominal wall to carry stool out of the body |
-tomy | Incision, cut into | Laparotomy | Celiotomy; abdominal surgery performed using an incision into the abdomen (Rajaretnam et al., 2023) |
Term | Definition | Audio |
---|---|---|
Cholangiocarcinoma | A group of cancers that affect the bile ducts that travel from the gallbladder to the liver and small intestine (Mayo Clinic, n.d.) | AUDIO |
Diverticulitis | Inflammation or infection of one or more diverticula in the digestive tract | AUDIO |
Duodenojejunostomy | A medical procedure that creates an opening between the duodenum and jejunum (for example, to bypass a constriction; Merriam-Webster, n.d.) | AUDIO |
Polypectomy | Removal of a polyp, such as precancerous polyps in the colon | AUDIO |
Steatohepatitis | Inflammation of the liver caused by excess fat buildup (Mayo Clinic, 2025) | AUDIO |
Xerostomia | Dry mouth | AUDIO |
Omphalocele | A medical condition in which a baby is born with their abdominal organs outside of their body (protruding); surgery is required to treat the condition; Cleveland Clinic, 2024) | AUDIO |
Cholelithiasis | The formation of gallstones in the gallbladder | AUDIO |
Osteomalacia | Softening of the bones, which can be caused by certain gastrointestinal conditions, such as celiac disease that can result in vitamin D malabsorption (Minisola et al., 2020) | AUDIO |
Diverticulosis | The condition of having diverticula in the colon | AUDIO |
Source: THIS TUTORIAL HAS BEEN ADAPTED FROM “OPEN RN | MEDICAL TERMINOLOGY – 2e” BY ERNSTMEYER & CHRISTMAN AT OPEN RESOURCES FOR NURSING (Open RN). ACCESS FOR FREE AT https://wtcs.pressbooks.pub/medterm/ LICENSING: CREATIVE COMMONS ATTRIBUTION 4.0 INTERNATIONAL.
REFERENCES
Anorectal Manometry. (2022, September 6). Cleveland Clinic. Anorectal Manometry: What It Is, Procedure Details & Results
Cholangiocarcinoma (Bile Duct Cancer). (n.d.). Mayo Clinic. Cholangiocarcinoma (bile duct cancer) - Symptoms and causes - Mayo Clinic
Merriam-Webster. (n.d.). Duodenojejunostomy. In Merriam-Webster.com medical dictionary. Retrieved July 3, 2025, from www.merriam-webster.com/medical/duodenojejunostomy
Metabolic Dysfunction-Associated Steatohepatitis (MASH). (2025, May 5). Cleveland Clinic. What Is Metabolic Dysfunction-Associated Steatohepatitis?
Harari, J. (2025). Yellow fat disease in cats and other animals. Merck Veterinary Manual, Professional Edition. Yellow Fat Disease in Cats and Other Animals - Musculoskeletal System - Merck Veterinary Manual
Omphalocele. (2025, July 11). Cleveland Clinic. Omphalocele: What it is, Causes, Treatment & Outlook
Minisola, S., Colangelo, L., Pepe, J., Diacinti, D., Cipriani, C., & Rao, S. D. (2020). Osteomalacia and vitamin D status: A clinical update 2020. JBMR plus, 5(1), e10447. doi.org/10.1002/jbm4.10447
Rajaretnam N, Okoye E, Burns B. Laparotomy. [Updated 2023 May 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: www.ncbi.nlm.nih.gov/books/NBK525961/