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Digestive System Terminology

Author: Sophia

what's covered
In this lesson, you will learn about digestive system terminology. You will learn new prefixes, combining forms, and suffixes that are helpful in building medical terms related to the digestive system. You will also practice using these word parts. Specifically, this lesson will cover:

Table of Contents

1. Introduction to Digestive System Terminology

In this lesson, you will learn terminology related to the digestive system.

The function of the digestive system is to break down the foods you eat, release their nutrients, and absorb those nutrients into the body. The digestive system is continually at work, but people often don’t appreciate the complex tasks it performs until something malfunctions. Consider what happens when you eat an apple. You enjoy the apple’s taste as you chew it, but in the hours that follow, unless something goes amiss and you get a stomachache, you don’t notice your digestive system is working. You may be working, studying, or sleeping, having forgotten all about the apple, but your stomach and intestines are busy digesting it. By the time any waste material is excreted, the body has absorbed all the nutrients it can use from the apple. In short, whether you pay attention or not, the organs of the digestive system perform their specific functions, allowing you to use the food you eat to provide energy for your daily activities.

The human digestive system includes the mouth, tongue, esophagus, stomach, small intestine, large intestine, ascending colon, transverse colon, descending colon, anus, liver, and gallbladder.

The figure above shows the basic structure of the human digestive tract. You will learn more about all of these structures later in this course. You can see the basic path traveled by food. Food enters the mouth, then travels through the tubular esophagus to the stomach, located around the middle of the trunk. The liver, an important organ with many functions, covers the top of the stomach and extends to the lower right side. The gallbladder is a smaller organ that is located just below the liver, with ducts extending to the liver and small intestine. The stomach connects to the small intestine, a long, tubular organ coiled in the lower abdomen. The small intestine connects to the large intestine, which rises along the right side of the abdomen (the ascending colon), runs horizontally across the abdomen above the small intestine and below the liver (the transverse colon), runs down the left side of the abdomen (the descending colon), and curves back below the small intestine before curving down to end at the anus, through which wastes exit the body. Note that the colon (including the ascending, transverse, and descending colon) makes up most of the large intestine. The pancreas is visible between the large intestine and stomach.



2. Prefixes

The table below shows common prefixes that you will encounter as you learn about the digestive system. Most of these should be familiar. Remember that many other prefixes are also used, including prefixes that you have already learned.

Term Definition Example Definition of Example
Dys- Abnormal Dysphagia Difficulty in swallowing
Endo- Within, in Esophagogastroduodenoscopy (EGD) Visualization of the esophagus, stomach, and duodenum (the first part of the intestine) using an endoscope, making it a type of endoscopy
Sub- Under, below Sublingual Under the tongue


3. Combining Forms

Many combining forms that you have already learned are relevant to learning about the digestive system. Some examples of familiar combining forms and a few new combining forms are in the table below. The table below focuses on combining forms that describe digestive system structures.

Term Definition Example Definition of Example
Abdomin/o Abdomen, abdominal Abdominal region Region of the abdomen
An/o Anus Anorectal manometry A medical test of the function of the muscles involved in producing a bowel movement (anal muscles, rectal muscles; Cleveland Clinic, 2023)
Append/o, appendic/o Appendix Appendicitis Inflammation of the appendix
Celi/o Abdomen, abdominal cavity Celiac disease A serious autoimmune disorder that can occur in genetically predisposed people, where the ingestion of gluten leads to damage in the small intestine.
Chol/e Gall, bile (a digestive fluid produced by the gallbladder that can emulsify lipids) Cholecystitis Inflammation of the gallbladder
Cholangi/o Bile duct Cholangiocarcinoma A group of cancers that affect the bile ducts that carry bile between the liver, gallbladder, and small intestine (Mayo Clinic, n.d.)
Col/o, colon/o Colon Colorectal cancer (CRC) A type of cancer that occurs in the colon or rectum
Diverticu/o Diverticulum (a small, bulging pouch that can form in the lining of the digestive system) Diverticulitis Inflammation or infection of one or more diverticula in the digestive tract
Duoden/o Duodenum (the first section of the small intestine, immediately beyond the stomach, leading to the jejunum) Duodenojejunostomy A medical procedure that creates an opening between the duodenum and jejunum (for example, to bypass a constriction; Merriam-Webster, n.d.)
Enter/o Intestine Enteritis Inflammation of the small intestine
Esophag/o Esophagus Esophagitis Inflammation of the esophagus
Gastr/o Stomach Gastritis Inflammation of the stomach
Hepat/o Liver Hepatitis Inflammation of the liver
Ile/o Ileum Ileocecal valve A sphincter muscle valve that separates the small intestine and the large intestine

try it
Let’s try some examples.
Based on the word parts, what does cholecystectomy mean?
Cholecystectomy means the removal of the gallbladder.
Break apart the word cholecystitis. Remember that cystitis is bladder inflammation (you encountered the term previously). What do you think the word parts mean?
Chol/e refers to the gallbladder. The suffix –itis means inflammation. Cyst/o must mean bladder if cyst/o + -itis means bladder inflammation. So cholecystitis means inflammation of the gallbladder, which is a sac, like the bladder.

Remember that you previously learned the word gastroenterology. Consider a similar word, gastroenteritis.
Based on the word parts, what does gastroenteritis mean?
Gastroenteritis has the word parts gastr/o (stomach) + enter/o (intestines) + -itis (inflammation). Gastroenteritis is inflammation of the stomach and intestines.

Here are more examples of combining forms that are useful to know as you learn about the digestive system.

Term Definition Example Definition of Example
Jejun/o Jejunum Duodenojejunostomy A medical procedure that creates an opening between the duodenum and jejunum (for example, to bypass a constriction; Merriam-Webster, n.d.)
Lingu/o Tongue Sublingual Under the tongue
Or/o Mouth Oral Pertaining to the mouth (e.g., oral medication is administered by mouth)
Pancreat/o Pancreas Pancreatitis Inflammation of the pancreas
Peritone/o Peritoneum Peritonitis Inflammation of the peritoneum
Polyp/o Polyp (a small growth) Polypectomy Removal of a polyp, such as precancerous polyps in the colon
Proct/o Rectum Proctologist A physician who specializes in diagnosing and treating disorders of the rectum and anus
Steat/o Fat Steatohepatitis Inflammation of the liver caused by excess fat buildup (Mayo Clinic, 2025)
Xer/o Dry Xerostomia Dry mouth

try it
Let’s try some examples. Steatitis is a condition that is a particular problem in cats, although other animals can develop it.
Based on the word parts, what does steatitis mean?
Steatitis is inflammation of fat tissue. It is likely caused by diet and can be very painful, but it can be resolved with dietary changes, vitamin E injections, and pain relief as needed (Harari, 2025).

Xerophytes are a specific type of plant. The combining form phyt/o and the suffix –phyte both mean plant.
Based on the word parts, what is a xerophyte?
Xerophyte means “dry plant.” Xerophytes are plants that thrive in dry environments.


4. Suffixes

In addition to prefixes and combining forms, there are many suffixes that are useful in discussing the digestive system. The table below includes familiar suffixes and a few new suffixes that will be helpful.

Term Definition Example Definition of Example
-cele Hernia, protrusion Omphalocele A medical condition in which a baby is born with their abdominal organs outside of their body (protruding); surgery is required to treat the condition; Cleveland Clinic, 2024)
-lith Stone Cholelithiasis The formation of gallstones (small, hard crystalline masses) in the gallbladder
-malacia Softening Osteomalacia Softening of the bones, which can be caused by certain gastrointestinal conditions, such as celiac disease, that can result in vitamin D malabsorption (Minisola et al., 2020)
-megaly Enlargement Hepatomegaly Enlargement of the liver
-osis Condition Diverticulosis The condition of having diverticula in the colon
-pepsia Digestion Dyspepsia Indigestion (marked by epigastric pain, burning, and nausea)
-phagia Eating or swallowing Dysphagia Difficulty in swallowing
-stomy Creating an opening Colostomy A surgical procedure that brings one end of the large intestine out through the abdominal wall to carry stool out of the body
-tomy Incision, cut into Laparotomy Celiotomy; abdominal surgery performed using an incision into the abdomen (Rajaretnam et al., 2023)

try it
Let’s try an example. You previously learned the term laryngostomy.
Break apart the word laryngostomy and use it to explain what the term means.
Laryngostomy means the creation of a laryngeal opening. The word parts are laryng/o (larynx) and -ostomy (creation of an opening).

terms to know
The table below lists terms that are especially important or that may be difficult to pronounce. Audio is provided to help you learn how to say these terms.

Term Definition Audio
Cholangiocarcinoma A group of cancers that affect the bile ducts that travel from the gallbladder to the liver and small intestine (Mayo Clinic, n.d.) AUDIO
Diverticulitis Inflammation or infection of one or more diverticula in the digestive tract AUDIO
Duodenojejunostomy A medical procedure that creates an opening between the duodenum and jejunum (for example, to bypass a constriction; Merriam-Webster, n.d.) AUDIO
Polypectomy Removal of a polyp, such as precancerous polyps in the colon AUDIO
Steatohepatitis Inflammation of the liver caused by excess fat buildup (Mayo Clinic, 2025) AUDIO
Xerostomia Dry mouth AUDIO
Omphalocele A medical condition in which a baby is born with their abdominal organs outside of their body (protruding); surgery is required to treat the condition; Cleveland Clinic, 2024) AUDIO
Cholelithiasis The formation of gallstones in the gallbladder AUDIO
Osteomalacia Softening of the bones, which can be caused by certain gastrointestinal conditions, such as celiac disease that can result in vitamin D malabsorption (Minisola et al., 2020) AUDIO
Diverticulosis The condition of having diverticula in the colon AUDIO

summary
In this lesson, you had an introduction to digestive system terminology. After a brief overview of the digestive system, you learned about prefixes, combining forms, and suffixes. This terminology will help you understand a variety of digestive system conditions and procedures.

Source: THIS TUTORIAL HAS BEEN ADAPTED FROM “OPEN RN | MEDICAL TERMINOLOGY – 2e” BY ERNSTMEYER & CHRISTMAN AT OPEN RESOURCES FOR NURSING (Open RN). ACCESS FOR FREE AT https://wtcs.pressbooks.pub/medterm/ LICENSING: CREATIVE COMMONS ATTRIBUTION 4.0 INTERNATIONAL.

REFERENCES

Anorectal Manometry. (2022, September 6). Cleveland Clinic. Anorectal Manometry: What It Is, Procedure Details & Results

Cholangiocarcinoma (Bile Duct Cancer). (n.d.). Mayo Clinic. Cholangiocarcinoma (bile duct cancer) - Symptoms and causes - Mayo Clinic

Merriam-Webster. (n.d.). Duodenojejunostomy. In Merriam-Webster.com medical dictionary. Retrieved July 3, 2025, from www.merriam-webster.com/medical/duodenojejunostomy

Metabolic Dysfunction-Associated Steatohepatitis (MASH). (2025, May 5). Cleveland Clinic. What Is Metabolic Dysfunction-Associated Steatohepatitis?

Harari, J. (2025). Yellow fat disease in cats and other animals. Merck Veterinary Manual, Professional Edition. Yellow Fat Disease in Cats and Other Animals - Musculoskeletal System - Merck Veterinary Manual

Omphalocele. (2025, July 11). Cleveland Clinic. Omphalocele: What it is, Causes, Treatment & Outlook

Minisola, S., Colangelo, L., Pepe, J., Diacinti, D., Cipriani, C., & Rao, S. D. (2020). Osteomalacia and vitamin D status: A clinical update 2020. JBMR plus, 5(1), e10447. doi.org/10.1002/jbm4.10447

Rajaretnam N, Okoye E, Burns B. Laparotomy. [Updated 2023 May 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: www.ncbi.nlm.nih.gov/books/NBK525961/

Attributions
  • Components of the Digestive System | Author: . Gordon Betts, Kelly A. Young, James A. Wise, Eddie Johnson, Brandon Poe, Dean H. Kruse, Oksana Korol, Jody E. Johnson, Mark Womble, Peter DeSaix | License: Creative Commons Attribution License
  • Blausen 0863 ToothAnatomy | Author: BruceBlaus | License: Creative Commons Attribution 3.0 Unported
Terms to Know
-cele

Hernia, protrusion.

-pepsia

Pertaining to digestion.

-phagia

Pertaining to eating or swallowing.

-stomy

Pertaining to creating an opening.

-tomy

Pertaining to an incision, cutting into.

Abdomin/o

Pertaining to the abdomen.

An/o

Pertaining to the anus.

Anus

The opening at the end of the digestive tract where feces leave the body.

Append/o

Pertaining to the appendix.

Appendic/o

Pertaining to the appendix.

Appendicitis

Inflammation of the appendix.

Ascending Colon

The first part of the colon which travels upward on the right side of the abdomen.

Bile

A digestive fluid produced by the gallbladder that can emulsify lipids.

Bile Duct

One of the ducts that carries bile between the liver, gallbladder, and small intestine.

Celi/o

Pertaining to the abdomen or abdominal cavity.

Celiac Disease

A serious autoimmune disorder that can occur in genetically predisposed people where the ingestion of gluten leads to damage in the small intestine.

Celiotomy

Also called laparotomy; abdominal surgery performed using an incision into the abdomen.

Chol/e

Pertaining to gall, bile.

Cholangi/o

Pertaining to a bile duct or bile ducts.

Cholangiocarcinoma

A group of cancers that affect the bile ducts that travel from the gallbladder to the liver and small intestine.

Cholecystitis

Inflammation of the gallbladder.

Cholelithiasis

The formation of gallstones in the gallbladder.

Col/o

Pertaining to the colon.

Colon

The largest part of the large intestine; includes the ascending colon, transverse colon, and descending colon.

Colon/o

Pertaining to the colon.

Colorectal Cancer (CRC)

A type of cancer that occurs in the colon or rectum.

Colostomy

A surgical procedure that brings one end of the large intestine out through the abdominal wall to carry stool out of the body.

Descending Colon

The part of the colon that travels downward on the left side of the abdomen.

Diverticul/o

Pertaining to a diverticulum or diverticula.

Diverticulitis

Inflammation or infection of one or more diverticula in the digestive tract.

Diverticulosis

The condition of having diverticula in the colon.

Diverticulum

A small, bulging pouch that can form in the lining of the digestive system.

Duoden/o

The first section of the small intestine, immediately beyond the stomach, leading to the jejunum.

Duodenojejunostomy

A medical procedure that creates an opening between the duodenum and jejunum (for example, to bypass a constriction).

Dyspepsia

Indigestion (marked by epigastric pain, burning, and nausea).

Endoscopy

Visualization of the esophagus, stomach, and duodenum (the first part of the intestine) using an endoscope.

Enter/o

Pertaining to the intestines.

Enteritis

Inflammation of the small intestine.

Esophag/o

Pertaining to the esophagus.

Esophagitis

Inflammation of the esophagus.

Gallbladder

A small organ where bile is stored, before it is released into the small intestine.

Gallstones

Small, hard, crystalline masses that form in the gallbladder.

Gastr/o

Pertaining to the stomach.

Gastritis

Inflammation of the stomach.

Gastroenteritis

Inflammation of the stomach and intestines.

Gastrointestinal (GI)

Pertaining to the stomach and intestines.

Hepat/o

Pertaining to the liver.

Hepatitis

Inflammation of the liver.

Ile/o

Pertaining to the ileum.

Ileocecal Valve

A sphincter muscle valve that separates the small intestine and the large intestine.

Jejun/o

Pertaining to the jejunum.

Jejunum

The middle part of the small intestine, between the duodenum and the ileum.

Laparotomy

Also called celiotomy; abdominal surgery performed using an incision into the abdomen.

Lingu/o

Pertaining to the tongue.

Omphalocele

A medical condition in which a baby is born with their abdominal organs outside of their body (protruding); surgery is required to treat the condition.

Or/o

Pertaining to the mouth.

Oral

Pertaining to the mouth (e.g., oral medication is administered by mouth).

Pancreas

A large gland behind the stomach which secretes digestive enzymes into the duodenum; it also produces hormones that regulate blood sugar.

Pancreat/o

Pertaining to the pancreas.

Pancreatitis

Inflammation of the pancreas.

Peritone/o

Pertaining to the peritoneum.

Peritonitis

Inflammation of the peritoneum.

Polyp

A small growth.

Polyp/o

Pertaining to a polyp or polyps.

Polypectomy

Removal of a polyp, such as precancerous polyps in the colon.

Proct/o

Pertaining to the rectum.

Proctologist

A physician who specializes in diagnosing and treating disorders of the rectum and anus.

Rectum

The final section of the large intestine, terminating at the anus.

Small Intestine

The part of the intestine where most of the digestion and absorption of food occurs, extending between the stomach and large intestine.

Steat/o

Pertaining to fat.

Steatitis

Inflammation of fat tissue.

Steatohepatitis

Inflammation of the liver caused by excess fat buildup.

Sublingual

Under the tongue.

Transverse Colon

The middle part of the colon which travels across the abdomen.